Lifelong Coprophagy in Male Mice

Studies on coprophagy in experimental animals.

. [2] Barnes, R.H. and Fiala, G. (1958). Effects of the prevention of coprophagy in the rat II. Vitamin B12 requirement.J. Nutr., 65, 103-114. [3] Barki., V.H., Derse, P.H., Collins, R.A., Hart, E.B., and Elevehjem, C.A. (1949). The influence of coprophagy on the biotin and folic acid requirements of the rat. J. Nutr., 37, 443-456. [4] Bjð±rnhag, G. (1981). Separationand retrograde tran...

Lifelong challenge of calcium homeostasis in male mice lacking TRPV5 leads to changes in bone and calcium metabolism

Trpv5 plays an important role in calcium (Ca2+) homeostasis, among others by mediating renal calcium reabsorption. Accordingly, Trpv5 deficiency strongly stresses Ca2+ homeostasis in order to maintain stable serum Ca2+. We addressed the impact of lifelong challenge of calcium homeostasis on the bone phenotype of these mice.Aging significantly increased serum 1,25(OH)2D3 and PTH levels in both g...

Effects of Coprophagy in Microtine Rodents

Coprophagy in leporids and other mammalian herbivores

Leporids have long been known to reingest soft faeces. However, it was recently found that they regularly reingest hard faeces, too. During the daytime, both soft and hard faeces are defecated and all of the faeces are reingested. Excreted at night are the hard faeces, which are normally discarded but reingested in starvation. The separation mechanism in the proximal colon, which diverts fine p...

Lifelong Caloric Restriction Increases Working Memory in Mice

Caloric restriction (CR) is argued to positively affect general health, longevity and the normally occurring age-related reduction of cognition. This issue is well examined, but most studies investigated the effect of short-term periods of CR. Herein, 4 weeks old female mice were fed caloric restricted for 4, 20 and especially for 74 weeks. CR mice received 60% of food eaten by their ad libitum...